The management of chronic pain represents a significant public health issue in the united states it is both costly to our health care system and devastating to the patients quality of life. Neuropathic pain develops as a result of lesions or disease affecting the somatosensory nervous system either in the periphery or centrally examples of neuropathic pain include painful polyneuropathy postherpetic neuralgia trigeminal neuralgia and post stroke pain. The key challenges in development of a targeted holistic approach to neuropathic pain management include appropriate diagnosis of the cause of pain identification of the type of pain and assessment of the importance of its various components and determination of appropriate treatment. An understanding of the mechanisms of neuropathic pain can provide the clinician scientist with a basic rationale for treatment because the pathogenesis of neuropathic pain has not been determined the practitioner must be aware of the various classes of pharmacotherapeutic agents that have been suggested to provide relief in selected cases pharmacotherapy for neuropathic pain encompasses a . Written by internationally renowned leaders in the fields of peripheral neuropathy and neuropathic pain this resource discusses the clinical approaches to diagnosis and treatment of neuropathic pain its underlying mechanisms and strategies for prevention
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